SS-31

SS-31, also known as elamipretide and MTP-131, is a synthetic tetrapeptide research compound identified by the sequence D-Arg-Dmt-Lys-Phe-NH₂.

The compound is represented in chemical and scientific reference databases under the CAS number 736992-21-5 and is classified as an oligopeptide. (pubchem.ncbi.nlm.nih.gov)

This product is supplied as a research material for qualified laboratory and scientific applications.

Product Classification

Primary Category: Research Peptides
Scientific Category: Mitochondria-Targeted Tetrapeptide
Secondary Category: Peptide Research Compounds
Product Type: Synthetic Research Peptide

Catalog Tags

SS-31 · Elamipretide · MTP-131 · Mitochondrial Research · Research Peptide · Tetrapeptide · Laboratory Research · Research Material

Chemical Information

Compound: SS-31
Established Name: Elamipretide
Alternative Designation: MTP-131 / Bendavia
Sequence: D-Arg-Dmt-Lys-Phe-NH₂ (RXKF)
CAS Number: 736992-21-5
Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Weight: Approximately 639.8 g/mol (pubchem.ncbi.nlm.nih.gov)

PubChem identifies elamipretide as a synthetic tetrapeptide and provides the chemical identifiers and molecular characteristics above. (pubchem.ncbi.nlm.nih.gov)

Research Information

SS-31 (elamipretide) is a synthetic tetrapeptide that has been investigated in scientific research involving mitochondrial biology and related experimental systems.

The compound has also undergone clinical development. Importantly, FDA approved FORZINITY (elamipretide) in September 2025 for a specific medical indication involving Barth syndrome. (fda.gov)

Accordingly, this research-material listing does not make claims regarding the approved drug, its indication, clinical efficacy, dosing, administration, or suitability for any medical condition.

The product description is limited to the identity and classification of the research material and does not represent the research material as an FDA-approved drug.

Research Applications

SS-31 may be examined in controlled laboratory and scientific environments for purposes such as:

Peptide characterization
Analytical testing
Structural investigation
Mitochondrial research
Molecular research
Comparative peptide studies
Laboratory assay development
Peptide-related experimental research

These statements describe potential research contexts only and do not constitute recommendations for administration to humans or animals.

Product Specifications

Product Name: SS-31
Established Name: Elamipretide
Alternative Name: MTP-131
Product Type: Synthetic research peptide
Primary Category: Research Peptides
Scientific Classification: Mitochondria-Targeted Tetrapeptide
Sequence: D-Arg-Dmt-Lys-Phe-NH₂
Sequence Code: RXKF
CAS: 736992-21-5
Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Weight: ~639.8 g/mol
Intended Application: Laboratory and scientific research (pubchem.ncbi.nlm.nih.gov)

Important Product Information

SS-31, elamipretide, and MTP-131 refer to the same active peptide compound in the references cited above.

Chemical form must be verified before publishing specifications. The free compound, acetate form, and TFA form are not interchangeable for purposes of chemical specifications. If the supplied material is specifically elamipretide acetate or elamipretide TFA, the product page should use the corresponding identity and molecular information rather than the free-compound specifications above. (pubchem.ncbi.nlm.nih.gov)

Product identity, purity, analytical results, salt form, and other batch-specific specifications should be verified against the applicable Certificate of Analysis (COA) where available.

Research Use Notice

This product is supplied solely as a research material for qualified laboratory and scientific use.

It is not intended for human consumption, human therapeutic use, veterinary use, diagnosis, treatment, mitigation, or prevention of disease.

Nothing on this product page should be interpreted as a recommendation or representation that this research material is intended to affect the structure or function of the human body.

Not for use as a drug, dietary supplement, food, cosmetic, or medical treatment.

For laboratory research purposes only.